Barcelona will secure top spot in their group with another positive result on Wednesday in what is arguably the biggest game of Champions League matchday five.
Lionel Messi is close to a personal milestone but Juventus will be desperate to avenge their 3-0 loss at Camp Nou and secure passage to the last 16 themselves.
Manchester United are also on the brink of the knockout phase and will look to fit-again Paul Pogba to improve on a pretty miserable record in the competition, while Paris Saint-Germain represent a daunting prospect for Celtic and Brendan Rodgers.
Chelsea will look to follow them into the next round and will hope Eden Hazard continues his electric form against Qarabag, while Atletico Madrid and Roma face off in a potentially pivotal showdown in the Spanish capital.
Below, we examine the key Opta numbers behind Wednesday's fixtures.
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